High rune is a term used by players for runes that are considered to be amongst the most valuable of them all. As they go higher in value, it gets more difficult to find D2R items , however, we have made this list to let you in on all the locations and bosses that drop them.
Secret Cow Level
One of the best places to farm high runes is without a doubt, the secret cow level. To access the secret level, however, you would need to have done some preparation. To create a portal to the Cow Level, you would first need to have killed the final boss of that difficulty and then combine a Wirt’s Leg and a Tome of Town Portal in the Horadric Cube while standing in the rogue encampment.